Endocrine Abstracts

Mrs XY, 29 years. (gravida: 3 and para 2) was admitted under the obstetricians with severe hyperemesis gravidarum (HG). An ultrasonogram revealed single live foetus of 8 weeks gestation. Her two previous pregnancies were normal with no history of HG. Mrs XY was on levothyroxine 150 μg OD for autoimmune primary hypothyroidism with TPO antibodies of 259 kU/l (0–5.6). She was also taking sertraline 200 mg OD for depression. The hyperemesis settled with i.v. fluids as we...

Mrs XY, 28 years. primigravida was seen for PV bleed. Ultrasonogram confirmed live intrauterine foetus of 8 weeks gestation with no obvious cause for PV bleeding. An OGTT at 21 weeks suggested gestational diabetes. She was referred to Diabetes Nurse led clinic and treated with metformin. Hypertension was recorded and controlled with labetalol and amlodipine. Mrs XY had recurrent admissions for PV bleeds and some polycythaemia. She was seen by the haematologist and a diagnosis ...

18 year old female referred with 2 years history of hirsutism and secondary amenorrhoea. She was born at 37 weeks and was found to have neonatal hypothermia, hypoglycaemia and crossed hemihypertrophy, but no macroglossia. Due to the increased risk of Wilm’s tumour she had regular ultrasound scans up to the age of 11 years. She attained menarche at the age of 13 but had only two periods within 18 months. By the age of 15 she developed hirsutism and acne. Biochemistry revea...

Introduction: Infertility affects 15% of couples worldwide. Male factors account for half of cases seeking medical care.Objectives and methods: To ascertain whether the American Association of Clinical Endocrinologists (AACE) guidelines regarding gonadotrophin induction of spermatogenesis in men with hypogonadism are being followed in our unit. Data were collected retrospectively from clinical records.Results: 26 couples were ident...